Optimisation of a payer value story to showcase the benefit of a treatment
Challenge
Manufacturer developed a cost-effectiveness model using published model structures based on the clinical trial:
Value story did not resonate with audience and key elements of value not included in economic model
The evaluation did not show the product to be cost-effective
Request
Review and revise value messages and optimise cost-effectiveness model
Response
- Detailed review of evidence and available data, and suggested potential post-hoc analyses
- Face-to-face interviews conducted with clinical experts to understand unmet need and potential value of the medicine
- New value story was developed with revised model structure to showcase the value of the treatment
- Real-world evidence (RWE) was used to plug data gaps with extensive clinical validation
- Multiple approaches and model adaptations developed for countries with different standard of care
